2. Anti-infection Metabolic Enzyme/Protease
  3. Virus Protease Endogenous Metabolite
  4. L-Lysine hydrochloride

L-Lysine hydrochloride  (Synonyms: 盐酸赖氨酸)

目录号: HY-N0470 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

L-lysine hydrochloride 人类必需的氨基酸，具有多种益处，可用于疱疹的研究，并能增加钙吸收，减少糖尿病相关疾病和改善肠道健康。

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L-Lysine hydrochloride Chemical Structure

L-Lysine hydrochloride Chemical Structure

CAS No. : 657-27-2

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规格 价格 是否有货 数量
10 mM * 1 mL in Water ￥220
In-stock
1 g ￥200
In-stock
5 g   询价  
10 g   询价  

* Please select Quantity before adding items.

L-Lysine hydrochloride 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

体内研究
(In Vivo)

L-lysine treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhances antioxidant activity. Pre- or post-treatment with L-lysine leads to significant decreases in the levels of malondialdehyde and nitric oxide, while significant enhancement is observed in the activities of antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase) and glutathione[1]. L-lysine supplementation almost completely ameliorates vascular calcification. Dietary L-lysine strongly suppresses plasma intact parathyroid hormone in adenine rats and supports a proper bone-vascular axis. The conserved orientation of the femoral apatite in group Lys also evidences the bone-protective effects of L-lysine. Dietary L-lysine elevates plasma alanine, proline, arginine, and homoarginine but not lysine[2]. The dose-dependent delay in gastric emptying observed in rats is confirmed in humans with an increase in halftime of gastric emptying of 4 min/g L-lysine. Moreover, a dose-dependent increase in intestinal fluid accumulation is observed (0.4 mL/min/g L-lysine)[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

182.65

Formula

C6H15ClN2O2
CAS 号
性状

固体

颜色

White to off-white

中文名称

盐酸赖氨酸
结构分类
初始来源

a genetically modified strain of Escherichia coli.
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Store at room temperature, keep dry and cool

In solvent -80°C 2 years
-20°C 1 year
溶解性数据
细胞实验： 

H2O 中的溶解度 : 100 mg/mL (547.50 mM; 超声助溶)

DMSO 中的溶解度 : < 1 mg/mL (insoluble or slightly soluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 5.4750 mL 27.3748 mL 54.7495 mL
5 mM 1.0950 mL 5.4750 mL 10.9499 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物实验：

以下溶解方案，请直接配制工作液。建议现用现配，在短期内尽快用完。 以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比； 如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶。

  • 方案 一

    请依序添加每种溶剂： PBS

    Solubility: 50 mg/mL (273.75 mM); 澄清溶液; 超声助溶

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳，请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。
纯度 & 产品资料

纯度: ≥98.0%

COA (281 KB) HNMR (266 KB)

产品使用指南 (1538 KB)
参考文献
Animal Administration
[1][2]

Rats: Nephrocalcinosis in 6-week-old male Wistar rats is induced by continuous injection of rat PTH 1-34 at a dosage of 40 μg/kg per day via an osmotic mini-pump for 50 hours. L-lysine HCl or glycine at a dose of 20 mmol/kg is administered via a gastric tube at 2 hours, 14 hours, 26 hours, and 38 hours after the implantation of the osmotic pump. At the indicated periods, Serum and urinary biochemical parameters, urea nitrogen, albumin, calcium, inorganic phosphate, and magnesium are determined by clinical diagnostic reagents[2].

Mice: Four groups of mice (10 in each group) are assessed. Group I is the control. Animals in groups II-IV are injected intraperitoneally with L-arginine hydrochloride (400 mg/kg body weight [bw]) for 3 days. Group III animals are orally pre-treated with L-lysine(10 mg/kg bw), whereas group IV animals are orally post-treated with L-lysine(10 mg/kg bw). Serum samples are subjected to amylase, lipase, transaminase, and interleukin-6 (IL-6) assays. The pancreas is excised to measure the levels of malondialdehyde, nitric oxide, catalase, superoxide dismutase, reduced glutathione, and glutathione peroxidase[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

L-Lysine hydrochloride 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.4750 mL 27.3748 mL 54.7495 mL 136.8738 mL
5 mM 1.0950 mL 5.4750 mL 10.9499 mL 27.3748 mL
10 mM 0.5475 mL 2.7375 mL 5.4750 mL 13.6874 mL
15 mM 0.3650 mL 1.8250 mL 3.6500 mL 9.1249 mL
20 mM 0.2737 mL 1.3687 mL 2.7375 mL 6.8437 mL
25 mM 0.2190 mL 1.0950 mL 2.1900 mL 5.4750 mL
30 mM 0.1825 mL 0.9125 mL 1.8250 mL 4.5625 mL
40 mM 0.1369 mL 0.6844 mL 1.3687 mL 3.4218 mL
50 mM 0.1095 mL 0.5475 mL 1.0950 mL 2.7375 mL
60 mM 0.0912 mL 0.4562 mL 0.9125 mL 2.2812 mL
80 mM 0.0684 mL 0.3422 mL 0.6844 mL 1.7109 mL
100 mM 0.0547 mL 0.2737 mL 0.5475 mL 1.3687 mL

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Lysine657-27-2盐酸赖氨酸Virus ProteaseEndogenous MetaboliteInhibitorinhibitorinhibit

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